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Phenotype Image Detail
Image
Caption Forestomach analysis of mice on a zinc-deficient diet. The wild type mouse shows a slightly thickened forestomach epithelium (A) with PCNA-positive nuclei restricted to the basal and suprabasal cell layers (B). Testm1Cro/Tes+ mouse forestomach shows upward and downward outgrowths (C) with abundant PCNA-positive nuclei in these areas (D). Testm1Cro/Testm1Cro mouse forestomach displays deep downgrowth and focal hyperplastic lesions (E) with abundant PCNA-positive nuclei in these areas (F). Scale bar, 100mm.
Copyright This image is from Drusco A, Proc Natl Acad Sci U S A 2005 Aug 2;102(31):10947-51. Copyright 2005 National Academy of Sciences, U.S.A. J:100181
Associated
Alleles
Symbol Name
Testm1Cro testin LIM domain protein; targeted mutation 1, Carlo M Croce
Associated
Genotypes
Allelic Composition Genetic Background
Testm1Cro/Testm1Cro involves: 129X1/SvJ * C57BL/6J
Testm1Cro/Tes+ involves: 129X1/SvJ * C57BL/6J
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory