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Phenotype Image Detail
Image
Caption More than 50% of 10 month old Dmdmdx/? Myod1tm1Jae/Myod1tm1Jae mice (mdx:MyoD-/-) exhibited visible fibrosis in the ventricular region (arrow in A and B). Masson trichrome-stained serial sections through mutant hearts revealed the fibrosis to be confined primarily to epicardial portions of the left ventricle (compare C and D to E) and in regions encompassed by hypertrophied myocytes (arrowhead in B). Magnification: B, x40; C-F, x20.
Copyright This image is from Megeney LA, Proc Natl Acad Sci U S A 1999 Jan 5;96(1):220-5. Copyright 1999 National Academy of Sciences, U.S.A. J:52248
Associated
Alleles
Symbol Name
Dmdmdx dystrophin, muscular dystrophy; X linked muscular dystrophy
Myod1tm1Jae myogenic differentiation 1; targeted mutation 1, Rudolf Jaenisch
Associated
Genotypes
Allelic Composition Genetic Background
Dmdmdx/?
Myod1tm1Jae/Myod1tm1Jae 		involves: 129S4/SvJae * C57BL/10ScSn
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
MGI 6.24 		The Jackson Laboratory