Phenotype Image Detail

Image

Caption

A and B: BrdU-labeled cells in 2 week old control (left) and Gt(ROSA)26Sor^tm1(Wnt4)Bhr/Gt(ROSA)26Sor⁺ Tg(Col2a1-cre)1Bhr/0 mutant mice. C: The fraction of chondrocytes in the proliferation zone (pz) that incorporated BrdU was 0.189+/-0.051 in control mice compared to 0.122+/-0.020 in mutants (P<0.001). The labeling percentage of the control was designated as 1.0, and the relative percentage of the mutant was calculated at 0.64.

Copyright

This image is from Lee HH, PLoS ONE 2007;2(5):e450, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:129327

Associated Alleles

Symbol	Name
Gt(ROSA)26Sor^tm1(Wnt4)Bhr	gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Richard R Behringer
Tg(Col2a1-cre)1Bhr	transgene insertion 1, Richard R Behringer

Associated Genotypes

Allelic Composition	Genetic Background
Gt(ROSA)26Sor^tm1(Wnt4)Bhr/Gt(ROSA)26Sor^+ Tg(Col2a1-cre)1Bhr/0	involves: 129S7/SvEvBrd * C57BL/6 * SJL