Phenotype Image Detail

Image

Caption

Analysis of the inflammatory cell infiltrate in dextran sodium sulfate-induced colitis of wild type (WT) and Retnlb^tm1Gdw/Retnlb^tm1Gdw (RELMbeta-/-) mice. F4/80 staining in the colon of wild type mice (A) or Retnlb^tm1Gdw/Retnlb^tm1Gdw mice (B) treated with 4% dextran sodium sulfate (DSS) for 2 days. Arrows indicate F4/80-positive macrophages at the base of colonic crypts. F4/80 staining of the colon of wild type (C) or mutant mice (D) treated with 4% DSS for 7 days. Magnification: x200. Abbreviations: M, mucosa; MM muscularis mucosa; SM, submucosa; MP, muscularis propria.

Copyright

This image is from McVay LD, J Clin Invest 2006 Nov 1;116(11):2914-2923 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:114507

Associated Alleles

Symbol	Name
Retnlb^tm1Gdw	resistin like beta; targeted mutation 1, Gary D Wu

Associated Genotypes

Allelic Composition	Genetic Background
Retnlb^tm1Gdw/Retnlb^tm1Gdw	involves: 129S/SvEv * C57BL/6