Phenotype Image Detail

Image

Caption

Ultrastructure of ventricular myocardium of wild-type (WT) (A) and Calr^tm1Mlk/Calr^tm1Mlk (KO) (B) hearts and of atrial myocardium of wild-type (C) and mutant (D) hearts. It is apparent that there is a substantial difference in the myofibrillar width between the wild-type and mutant phenotypes in both ventricles and atria at late stages of development. Magnification 15,000x.

Copyright

This image is from Lozyk MD, BMC Dev Biol 2006;6():54, an open-access article, licensee BioMed Central Ltd. J:119647

Associated Alleles

Symbol	Name
Calr^tm1Mlk	calreticulin; targeted mutation 1, Marek Michalak

Associated Genotypes

Allelic Composition	Genetic Background
Calr^tm1Mlk/Calr^tm1Mlk	involves: 129S4/SvJae * C57BL/6J