Phenotype Image Detail

Image

Caption

A and B: Righting reflex (A) and mid-air righting (B) of wild type, Foxp2^tm1Momo/Foxp2^tm1Momo (homozygote) and Foxp2^tm1Momo/Foxp2⁺ (heterozygote) mice. C: Real-time spectrography of the ultrasonic vocalizations (USVs) of pups (P8) after separation from the dam. D: Major vocalization patterns (P8). Wild type vocalization was mainly whistle-type USVs, whereas heterozygous mice produced three major vocalization patterns including USVs similar to the wild type (Top), short-length USVs (Middle), and click-type sonic vocalization (Bottom). Homozygous mice showed only a small number of click-type vocalizations. E: Number of whistle-type USVs of pups (P8) per minute. Vocalizations were recorded for 3-5 min.

Copyright

This image is from Fujita E, Proc Natl Acad Sci U S A 2008 Feb 26;105(8):3117-22. Copyright 2008 National Academy of Sciences, U.S.A. J:132813

Associated Alleles

Symbol	Name
Foxp2^tm1Momo	forkhead box P2; targeted mutation 1, Takashi Momoi

Associated Genotypes

Allelic Composition	Genetic Background
Foxp2^tm1Momo/Foxp2^tm1Momo	involves: 129S6/SvEvTac * C57BL/6
Foxp2^tm1Momo/Foxp2^+	involves: 129S6/SvEvTac * C57BL/6