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Phenotype Image Detail
Image
Caption Sagittal sections of 12.5 dpc wild type (B) and Sox2tm1Rlb/Sox2+ (C) embryos showing bifurcation of the pouch in the mutant embryo. (D and E) Pituitary transverse sections of 5-week-old wild-type (D) and heterozygous mice (E). Note the presence of an extra cleft in the heterozygous pituitary (arrow). HYP, presumptive hypothalamus; RP, Rathke's pouch. Scale bars: 0.1 mm.
Copyright This image is from Kelberman D, J Clin Invest 2006 Sep;116(9):2442-55 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:114458
Associated
Alleles
Symbol Name
Sox2tm1Rlb SRY (sex determining region Y)-box 2; targeted mutation 1, Robin Lovell-Badge
Associated
Genotypes
Allelic Composition Genetic Background
Sox2tm1Rlb/Sox2+ involves: 129S/SvEv * MF1
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/12/2024
MGI 6.24 		The Jackson Laboratory