Phenotype Image Detail

Image

Caption

(a) Lung of Gba1^tm1Rlp/Gba1^tm1Rlp mice showed scattered inflammatory cell aggregations (arrows) in the mesenchyme. (b) Lung of wild type mice showed no signs of inflammation. (c and d) Skin sections of mutant (c) and wild type (d) mice. Stratum corneum (SC) and epidermis (ED) of mutant mice were thicker than those of wild type mice. Inflammatory cell infiltration was distinguished in upper dermis (DER) of mutant mice (arrows) Bars = 50um.

Copyright

This image is from Mizukami H, J Clin Invest 2002 May;109(9):1215-21 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:76409

Associated Alleles

Symbol	Name
Gba1^tm1Rlp	glucosylceramidase beta 1; targeted mutation 1, Richard L Proia

Associated Genotypes

Allelic Composition	Genetic Background
Gba1^tm1Rlp/Gba1^tm1Rlp	involves: 129S4/SvJae * C57BL/6