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Caption | Ultrastructure of epidermis. Sections of normal (A,D and F) and Tgm1tm1Kfyn/Tgm1tm1Kfyn (B,C,E and G) mouse epidermis at 18.5 dpc. C in A, cornified cell; arrow in the inset of A, cell envelope; K in A, keratohyalin F-granule in the stratum granulosum; K in B, a swollen Keratohyalin F-granule; arrows in B and C, abnormal electron-dense aggregates adherent or close to the plasma membrane. (D-G) Section of stratum corneum labeled with anti-loricrin antibody and 10 nm gold. Arrowheads in D, cell envelope; arrows in E, abnormal electron-dense aggregates; arrowheads in E, cell membrane. (F and G) Sections digested with proteases. (x12,200 in A and B; x28,400 in the inset of A and in C; x19,500 in D-G. Bar, 0.8um in A and B; 0.34um in the inset of A and in C; 0.5um in D-G.) | ||||
Copyright | This image is from Matsuki M, Proc Natl Acad Sci U S A 1998 Feb 3;95(3):1044-9. Copyright 1998 National Academy of Sciences, U.S.A. J:45653 | ||||
Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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