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Phenotype Image Detail
Image
Caption Electron microscopy of ascending aortic cross-sections from wild type (+/+, C and E) and Elntm1Dyl/Eln+ (+/-, D and F) mice at birth. Subendothelial (C and D) and medial sections (E and F) for both genotypes are compared. in wild type aortae, circumferentially oriented smooth muscle cells are interposed between well developed elastic lamellae. Note that elastic lamellae are abnormal and ~50% thinner in heterozygous mutant aortae. Bar, 3.0um.
Copyright This image is from Li DY, J Clin Invest 1998 Nov 15;102(10):1783-7 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:51109
Associated
Alleles
Symbol Name
Elntm1Dyl elastin; targeted mutation 1, Dean Y Li
Associated
Genotypes
Allelic Composition Genetic Background
Elntm1Dyl/Eln+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
MGI 6.24 		The Jackson Laboratory