Phenotype Image Detail

Image

Caption

Tumors occuring in Tsc2^tm1Djk/Tsc2⁺ mice. A-C: Renal lesions. A: Gross external appearance, at 15 months of age. B: Cyst lesion. C: Solid adenoma. D: Liver hemangioma. E: Lung adenoma. F: Angiosarcoma of extremity. Scale bars: A, 4mm; B,C and E, 60um; D, 25um.

Copyright

This image is from Onda H, J Clin Invest 1999 Sep;104(6):687-95 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:57631

Associated Alleles

Symbol	Name
Tsc2^tm1Djk	TSC complex subunit 2; targeted mutation 1, David J Kwiatkowski

Associated Genotypes

Allelic Composition	Genetic Background
Tsc2^tm1Djk/Tsc2^+	either: (involves: 129S4/SvJae * BALB/cJ) or (involves: 129S4/SvJae * Black Swiss) or (involves: 129S4/SvJae * C57BL/6J)