Phenotype Image Detail

Image

Caption

Nine month old Hexb^tm1Rlp/Hexb^tm1Rlp B4galnt1^tm1Rlp/B4galnt1^tm1Rlp (Hexb-/- GalNAcT-/-) with an age-matched B4galnt1^tm1Rlp/B4galnt1^tm1Rlp (Hexb+/+ GalNAcT-/-) mouse. Note the hunched posture and disheveled condition of the double mutant mouse.

Copyright

This image is from Liu Y, J Clin Invest 1999 Feb;103(4):497-505 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:53080

Associated Alleles

Symbol	Name
B4galnt1^tm1Rlp	beta-1,4-N-acetyl-galactosaminyl transferase 1; targeted mutation 1, Richard L Proia
Hexb^tm1Rlp	hexosaminidase B; targeted mutation 1, Richard L Proia

Associated Genotypes

Allelic Composition	Genetic Background
B4galnt1^tm1Rlp/B4galnt1^tm1Rlp Hexb^tm1Rlp/Hexb^tm1Rlp	involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6