Phenotype Image Detail

Image

Caption

Higher magnification views of the base of the declive in mea/mea cerebellum. Arrowheads in Figure 1B,E and H point to areas enlarged in B, B, and C, respectively. A-C: Cortical layers are deranged on the left (anterior aspect), yet, because of the infolding of the foliation pattern, they face normal cortical regions on the right (base of a folium in the posterior cerebellum). Granule cells are diminished in number (arrow, A) compared to the normal granule layer (A, igl). Purkinje cells are disoriented and project dendrites into the white matter tracts (arrows, B). Bergmann glial fibers are disoriented (arrows, C). Bar in C for A-C, 50um.

Copyright

This image is from Ross ME, Proc Natl Acad Sci U S A 1990 Jun;87(11):4189-92. Copyright 1990 National Academy of Sciences, U.S.A. J:28105

Associated Alleles

Symbol	Name
mea	meander tail

Associated Genotypes

Allelic Composition	Genetic Background
mea/mea	involves: STOCK Tyrp1^b Tyr^c-ch Mitf^Mi a^t Adamts20^bt