Phenotype Image Detail

Image

Caption

A: Representative radiographs of jaws show a lower mineral content in the Dmp1^tm1Mis/Dmp1^tm1Mis (KO, right panel) compared with the wild type control (WT, left panel), although mineral in surrounding bone appears increased in the mutant pup (arrow). B: Hematoxylin and eosin stainings of first molar indicate an overall reduction in layers of dentin (d) and enamel (e) in the mutant tooth compared with the control.

Copyright

This image is from Ye L, J Biol Chem 2004 Apr 30;279(18):19141-8 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:89498

Associated Alleles

Symbol	Name
Dmp1^tm1Mis	dentin matrix protein 1; targeted mutation 1, Yuji Mishina

Associated Genotypes

Allelic Composition	Genetic Background
Dmp1^tm1Mis/Dmp1^tm1Mis	involves: 129S7/SvEvBrd * C57BL/6