Phenotype Image Detail

Image

Caption

Immunostaining of Dspp^tm1Kul/Dspp^tm1Kul mouse tooth sections with biglycan (A) and decorin (B) shows accumulation around calcospherites. Scanning electron microscopy of the fractured teeth (C) showing the void spaces (*) in the dentin similar to the lightly stained regions (unmineralized) in hematoxylin and eosin stained teeth (D). cal, calcospherites.

Copyright

This image is from Sreenath T, J Biol Chem 2003 Jul 4;278(27):24874-80 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:84378

Associated Alleles

Symbol	Name
Dspp^tm1Kul	dentin sialophosphoprotein; targeted mutation 1, Ashok B Kulkarni

Associated Genotypes

Allelic Composition	Genetic Background
Dspp^tm1Kul/Dspp^tm1Kul	involves: 129/Sv * C57BL/6