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Phenotype Image Detail
Image
Caption The presence of craniorachischisis in Vangl2Lp/Vangl2Lp (Vangl2lp/lp, E) and in Vangl1Gt(XL802)Byg/Vangl1+ Vangl2Lp/Vangl2+ (Vangl1gt/+ Vangl2lp/+, F and arrows in C and D) double heterozygote embryos is compared with phenotypically normal Vangl1Gt(XL802)Byg/Vangl1+ controls (A and B). E13.5 embryos are shown in A-D. E18.5 fetuses are shown in E and F. B and D are dorsal views of embryos in A and C. Closed vs. open eyelid is identified by white arrows in E and F.
Copyright This image is from Torban E, Proc Natl Acad Sci U S A 2008 Mar 4;105(9):3449-54. Copyright 2008 National Academy of Sciences, U.S.A. J:132697
Associated
Alleles
Symbol Name
Vangl1Gt(XL802)Byg VANGL planar cell polarity 1; gene trap XL802, BayGenomics
Associated
Genotypes
Allelic Composition Genetic Background
Vangl2Lp/Vangl2Lp LPT/LeJ
Vangl1Gt(XL802)Byg/Vangl1+
Vangl2Lp/Vangl2+ 		involves: 129P2/OlaHsd * C57BL/6J * LPT/LeJ
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/12/2024
MGI 6.24 		The Jackson Laboratory