Phenotype Image Detail

Image

Caption

A: Histology of inflammatory lesions in lung, heart, liver and stomach of Tgfb1^tm1Jmu/Tgfb1^tm1Jmu (Tgfb1^RGE/RGE) mice (hematoxylin and eosin staining). B: Kaplan-Meier survival curve for mutant mice (n=54). C: Increased expression of Itgb6 protein in stomach and lung epithelium of mutant mice.

Copyright

This image is from Yang Z, J Cell Biol 2007 Mar 12;176(6):787-93, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:120085

Associated Alleles

Symbol	Name
Tgfb1^tm1Jmu	transforming growth factor, beta 1; targeted mutation 1, John Munger

Associated Genotypes

Allelic Composition	Genetic Background
Tgfb1^tm1Jmu/Tgfb1^tm1Jmu	involves: 129S6/SvEvTac * C57BL/6
Tg(Six2-EGFP/cre)1Amc/0 Vhl^tm1Jae/Vhl^tm1Jae	involves: 129S4/SvJae * CD-1