Phenotype Image Detail

Image

Caption

A: Intestinal tract of an 18 day old Slc12a2^tm1Ges/Slc12a2^tm1Ges mouse. Note the large focal hemorrhage in the cecum (arrow). B: Section through cecum of the same mutant mouse showing blood within the lumen (arrow). C and D: Higher magnification views of the regions boxed in B with broken (C) or solid (D) lines. Note red blood cells within the lumen (arrowhead in C) and evidence of extensive bleeding and pooling of blood in the interstitium (C and D).

Copyright

This image is from Flagella M, J Biol Chem 1999 Sep 17;274(38):26946-55 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:57651

Associated Alleles

Symbol	Name
Slc12a2^tm1Ges	solute carrier family 12, member 2; targeted mutation 1, Gary E Shull

Associated Genotypes

Allelic Composition	Genetic Background
Slc12a2^tm1Ges/Slc12a2^tm1Ges	Not Specified
Slc12a2^tm1Ges/Slc12a2^tm1Ges	involves: NMRI
Slc12a2^tm1Ges/Slc12a2^tm1Ges	FVB.129(Cg)-Slc12a2^tm1Ges