Phenotype Image Detail

Image

Caption

Gross phenotype of Slc4a2^tm1Ges/Slc4a2^tm1Ges mice. A: Compared with gender-matched wild type (+/+, upper) littermates, 18 day old Slc4a2^tm1Ges/Slc4a2^tm1Ges (-/-, lower) mice exhibited growth retardation and emaciation. B: In contrast to gender-matched wild type littermates, mutant mice lack incisor tooth eruption. C: Survival curve for wild type (n = 126) and mutant (n = 33) mice. The percentage of surviving mice was poltted against age in days, with day 0 being the day of birth.

Copyright

This image is from Gawenis LR, J Biol Chem 2004 Jul 16;279(29):30531-9 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:91617

Associated Alleles

Symbol	Name
Slc4a2^tm1Ges	solute carrier family 4 (anion exchanger), member 2; targeted mutation 1, Gary E Shull

Associated Genotypes

Allelic Composition	Genetic Background
Slc4a2^tm1Ges/Slc4a2^tm1Ges	involves: 129S6/SvEvTac * Black Swiss