Phenotype Image Detail

Image

Caption

A and B: Sagittal sections from E16.5 wild type (B⁺/B⁺) and Myh10^{tm6(Myh9/GFP)Rsad}/Myh10^{tm6(Myh9/GFP)Rsad} (B^a*/B^a*) mice. Note that the pontine neurons (arrow in A) are absent from their normal destination in mutant mice (arrow in B). Double arrows in B show the abnormal protrusion of facial neurons into the fourth ventricle of mutant mice. Scale bar, 100um. C and D: Sagittal sections from 7 month old wild type (C) and mutant mouse (D) cerebellums showing only minor alterations in the foliation pattern in the mutant brain. The arrowhead in C indicates a groove that is not present in the mutant brain. The arrow in the lower part of D points to abnormally protruding facial neurons. Scale bar, 500um.

Copyright

This image is from Bao J, J Biol Chem 2007 Jul 27;282(30):22102-11 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:124610

Associated Alleles

Symbol	Name
Myh10^tm6(Myh9/GFP)Rsad	myosin, heavy polypeptide 10, non-muscle; targeted mutation 6, Robert S Adelstein

Associated Genotypes

Allelic Composition	Genetic Background
Myh10^tm6(Myh9/GFP)Rsad/Myh10^tm6(Myh9/GFP)Rsad	involves: 129S6/SvEvTac * C57BL/6