Phenotype Image Detail

Image

Caption

Histology of connective tissue in tails of wild type, Fmod^tm1Aol/Fmod⁺ and Fmod^tm1Aol/Fmod^tm1Aol mice. Hematoxylin/chromotrope stained sections of tails from wild type (+/+, A-C), Fmod^tm1Aol/Fmod⁺ (+/-, D-F) and Fmod^tm1Aol/Fmod^tm1Aol (-/- G-I) littermates. A,B,D,E,G and H, transverse sections. C,F and I, longitudinal sections. d, dermis; m, muscle; t, tendon; are indicated. Photomicrographs A,D and G show an overview (magnification, x31). Micrographs B,C,E,F,H and I show tendon bundles at higher magnifications (x78). Arrows indicate abnormal fiber bundle in heterozygous tail.

Copyright

This image is from Svensson L, J Biol Chem 1999 Apr 2;274(14):9636-47 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:54069

Associated Alleles

Symbol	Name
Fmod^tm1Aol	fibromodulin; targeted mutation 1, Ake Oldberg

Associated Genotypes

Allelic Composition	Genetic Background
Fmod^tm1Aol/Fmod^tm1Aol	involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Fmod^tm1Aol/Fmod^+	involves: 129S1/Sv * 129X1/SvJ * C57BL/6