Phenotype Image Detail

Image

Caption

Lung histology in control (A) and Sftpc^tm1Swg/Sftpc^tm1Swg mice (B) demonstrate the extensive loss of alveoli at 1 year of age. Macrophage infiltrates are observed in the central and lower regions of B.

Copyright

This image is from Glasser SW, J Biol Chem 2003 Apr 18;278(16):14291-8 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:82925

Associated Alleles

Symbol	Name
Sftpc^tm1Swg	surfactant associated protein C; targeted mutation 1, Stephan W Glasser

Associated Genotypes

Allelic Composition	Genetic Background
Sftpc^tm1Swg/Sftpc^tm1Swg	either: 129 or (involves: 129 * Black Swiss)
Sftpc^tm1Swg/Sftpc^tm1Swg	involves: 129/Sv * Black Swiss