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Caption | Ultrathin-section electron micrographs of stereocilia of cochlear outer hair cells of wild type and Rdxtm1Sts/Rdxtm1Sts mice at 3 weeks of age. A: Low power electron micrographs. All of the wild type (Rdx+/+) hair cells bear numerous stereocilia with normal appearance, whereas Rdxtm1Sts/Rdxtm1Sts (Rdx-/-) hair cells were frequently characterized by abnormal 1-3 residual knoblike cellular protrusions on their apical surfaces. B: Wild type radixin-based stereocilia (A) and mutant ezrin-based stereocilia at various degeneration stages (B-D). Mutant ezrin-based stereocilia contained highly organized bundles of actin filaments as cores (B) that were indistinguishable in appearance from those in wild type radixin-based stereocilia (A), and during the process of degeneration, these stereocilia as well as core bundles appeared to be fused to form abnormal thick and short protrusions (C and D). Bars, 0.5um. | ||||
Copyright | This image is from Kitajiri S, J Cell Biol 2004 Aug 16;166(4):559-70, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:124151 | ||||
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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