Phenotype Image Detail

Image

Caption

A: Gross appearance of adrenal glands from male wild type (+/+), Soat1^tm1Far/Soat1⁺ (+/-), and Soat1^tm1Far/Soat1^tm1Far (-/-) mice. The scale at the bottom of the photograph is in millimeters. B: Oil red O-stained sections showing absence of neutral lipids in adrenal cortex of male homozygous mice. Identical findings were observed in female mice. Staining in the heterozygous mice was consistently confined to a smaller area of the zona fasciculata.

Copyright

This image is from Meiner VL, Proc Natl Acad Sci U S A 1996 Nov 26;93(24):14041-6. Copyright 1996 National Academy of Sciences, U.S.A. J:37049

Associated Alleles

Symbol	Name
Soat1^tm1Far	sterol O-acyltransferase 1; targeted mutation 1, Bob Farese

Associated Genotypes

Allelic Composition	Genetic Background
Soat1^tm1Far/Soat1^tm1Far	involves: 129S4/SvJae * C57BL/6