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Caption | A: Epidermis from a 2 day old wild type mouse. B: Epidermis from a Dsc1tm1Dga/Dsc1tm1Dga littermate showing hyperplasia. Bars (E) indicate thickness of living layers of epidermis. C: Epidermis from a mutant mouse showing localized hyperkeratosis and parakeratosis (retention of nuclei in the cornified layer) (arrow). D: Expression of Ki67 in the epidermis of a wild type mouse. E: Ki67 staining in the epidermis of a mutant mouse. Only one proliferating cell located in the basal layer is present in D (arrow), whereas in E almost all of the cells in the basal layer and numerous suprabasal cells (arrows) are undergoing cell division. A-C show head skin; D and E show back skin. Bars: A-C, 100um; D and E, 50um. | ||||
Copyright | This image is from Chidgey M, J Cell Biol 2001 Nov 26;155(5):821-32, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:73102 | ||||
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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