Phenotype Image Detail

Image

Caption

A,B: Total body fat mass (A) and total body lean mass (B) from mice fed a Western diet. n=3-10 mice per group. Data shown are means +/- SEM. C: Transverse abdominal cross-sections of a Scd1^ab-2J/Scd1^ab-2J Ldlr^tm1Her/Ldlr^tm1Her (Scd1(-/-)Ldlr(-/-), right) and a control (Ldlr^tm1Her/Ldlr^tm1Her, left) mouse obtained by magnetic imaging. Slices (1.5mm thick) at the kidneys were identified in sagittal images from each mouse. Fatty tissues are shown as bright areas. Spinal muscle, kidneys and subcutaneous (SC) and visceral (V) fat are indicated.

Copyright

This image is from MacDonald ML, J Lipid Res 2008 Jan;49(1):217-29 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text is from JLR. J:130278

Associated Alleles

Symbol	Name
Ldlr^tm1Her	low density lipoprotein receptor; targeted mutation 1, Joachim Herz
Scd1^ab-2J	stearoyl-Coenzyme A desaturase 1; asebia 2 Jackson

Associated Genotypes

Allelic Composition	Genetic Background
Ldlr^tm1Her/Ldlr^tm1Her	B6.129S7-Ldlr^tm1Her
Ldlr^tm1Her/Ldlr^tm1Her Scd1^ab-2J/Scd1^ab-2J	B6.Cg-Ldlr^tm1Her Scd1^ab-2J