Phenotype Image Detail

Image

Caption

A,B: Livers of female Ldlr^tm1Her/Ldlr^tm1Her (Scd1(+/+) Ldlr(-/-), A) and Scd1^ab-2J/Scd1^ab-2J Ldlr^tm1Her/Ldlr^tm1Her (Scd1(-/-)Ldlr(-/-), B) mice fed a Western diet stained with Oil Red O. C: Liver triglyceride (TG), free cholesterol (FC), and cholesteryl ester (CE) contents of single and double homozygous mice fed a Western diet. Data shown are means +/- SEM. n=8 mice per group.

Copyright

This image is from MacDonald ML, J Lipid Res 2008 Jan;49(1):217-29 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text is from JLR. J:130278

Associated Alleles

Symbol	Name
Ldlr^tm1Her	low density lipoprotein receptor; targeted mutation 1, Joachim Herz
Scd1^ab-2J	stearoyl-Coenzyme A desaturase 1; asebia 2 Jackson

Associated Genotypes

Allelic Composition	Genetic Background
Ldlr^tm1Her/Ldlr^tm1Her	B6.129S7-Ldlr^tm1Her
Ldlr^tm1Her/Ldlr^tm1Her Scd1^ab-2J/Scd1^ab-2J	B6.Cg-Ldlr^tm1Her Scd1^ab-2J