Phenotype Image Detail

Image

Caption

A: A slit lamp photo shows the dominant lamellar cataract of a Crygb^Clapper/Crygb⁺ (I4F/+) mouse at adulthood (indicated by arrows). B: A set of fresh lenses from wild type (+/+), heterozygous, and Crygb^Clapper/Crygb^Clapper (I4F/I4F) littermates at 3 weeks old. Scale bar, 1mm. Photos show retinal fundus (C1-C3), angiography (D1-D3), and the lenses (E1-E3) of a 30 day old wild type (C1, D1 and E1), a 21 day old homozygous mouse (C2,D2 and E2), a 3 month old homozygous mouse for the lens and fundus images (C3 and E3), and a 6 month old homozygous mouse for the angiography (D3). White arrowheads indicate retinal vessels. Scale bar, 1mm for lenses.

Copyright

This image is from Liu H, J Biol Chem 2005 Jul 1;280(26):25071-8 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:100851

Associated Alleles

Symbol	Name
Crygb^Clapper	crystallin, gamma B; Clapper

Associated Genotypes

Allelic Composition	Genetic Background
Crygb^Clapper/Crygb^Clapper	C57BL/6J-Crygb^Clapper
Crygb^Clapper/Crygb^+	C57BL/6J-Crygb^Clapper