Phenotype Image Detail

Image

Caption

A: Heart weight/body weight ratio of Lama4^tm1Ktry/Lama4^tm1Ktry mice and their littermate controls, at the age of 16 and 40 weeks. Filled bars, mutants; empty bars, littermate controls, mean +/- S.E; **, p<0.001. B: Immunofluorescence staining with anti-dystrophin monoclonal antibody (green) and Hoechst nuclear counter stain (blue) on cryostat sections from a mutant mouse heart at the age of 40 weeks and its littermate control heart. Cross-section area of cardiomyocytes was marked for quantification. Scale bar: 40um. C: Quantification of cardiomyocyte cross-section area from three mutant hearts at the age of 40 weeks (filled bar) and three littermate control hearts (empty bar), mean +/- S.E.; *, p<0.05.

Copyright

This image is from Wang J, J Biol Chem 2006 Jan 6;281(1):213-20 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:105789

Associated Alleles

Symbol	Name
Lama4^tm1Ktry	laminin, alpha 4; targeted mutation 1, Karl Tryggvason

Associated Genotypes

Allelic Composition	Genetic Background
Lama4^tm1Ktry/Lama4^tm1Ktry	B6.129X1-Lama4^tm1Ktry