Phenotype Image Detail

Image

Caption

A: M-mode echocardiography showing dilated left ventricle end diastole and systole in Lama4^tm1Ktry/Lama4^tm1Ktry(Lama4-/-) heart in comparison with control heart. B-E: Cumulative evaluation of cardiac function in 12 mutant and 12 age-matched control mice, showing heart rate (HR) in beats/minute. LVIDd in mm, LVIDs in mm, %FS and LVM in mg. Filled bar, mutants; empty bar, controls; mean +/- S.E.; *,p<0.05; **, p<0.01.

Copyright

This image is from Wang J, J Biol Chem 2006 Jan 6;281(1):213-20 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:105789

Associated Alleles

Symbol	Name
Lama4^tm1Ktry	laminin, alpha 4; targeted mutation 1, Karl Tryggvason

Associated Genotypes

Allelic Composition	Genetic Background
Lama4^tm1Ktry/Lama4^tm1Ktry	B6.129X1-Lama4^tm1Ktry