Phenotype Image Detail

Image

Caption

Phenotype of adult lens. A and B: Photograph of eyes of wild-type (+/+, A) and Ccn3^tm1Cabo/Ccn3^tm1Cabo (-/-, B) adult mice at 6 months of age, showing cataracts in both eyes in the mutant. The small white coloration in the wild-type eye is an artefact due to reflected light. C-F: Hematoxylin and eosin stained sections of wild-type (C and E) and mutant (D and F) adult eyes showing degeneration of the mutant lens, with vacuolation and loss of surface epithelium. Scale bars, C and D, 15um; E and F, 5um.

Copyright

This image is from Heath E, BMC Dev Biol 2008;8():18, an open-access article, licensee BioMed Central Ltd. J:135676

Associated Alleles

Symbol	Name
Ccn3^tm1Cabo	cellular communication network factor 3; targeted mutation 1, Catherine A Boulter

Associated Genotypes

Allelic Composition	Genetic Background
Ccn3^tm1Cabo/Ccn3^tm1Cabo	involves: 129S/SvEv