Phenotype Image Detail

Image

Caption

A: Control littermate S1pr2^tm1Rlp/S1pr2⁺ S1pr3^tm1Rlp/S1pr3^tm1Rlp (S1P 2^+/- S1P 3^-/-) embryo at E13.5. B: S1pr2^tm1Rlp/S1pr2^tm1Rlp S1pr3^tm1Rlp/S1pr3^tm1Rlp (S1P 1^-/- S1P 3^-/-) double homozygous mutant embryo at E13.5. C: Double homozygous mutant embryo at E14.5. D: Double homozygous mutant embryo at E15.5.

Copyright

This image is from Kono M, J Biol Chem 2004 Jul 9;279(28):29367-73 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:106055

Associated Alleles

Symbol	Name
S1pr2^tm1Rlp	sphingosine-1-phosphate receptor 2; targeted mutation 1, Richard L Proia
S1pr3^tm1Rlp	sphingosine-1-phosphate receptor 3; targeted mutation 1, Richard L Proia

Associated Genotypes

Allelic Composition	Genetic Background
S1pr3^tm1Rlp/S1pr3^tm1Rlp S1pr2^tm1Rlp/S1pr2^tm1Rlp	involves: 129S6/SvEvTac * C57BL/6