Phenotype Image Detail

Image

Caption

A mating between Atp2a1^tm1Dhm/Atp2a1⁺ parents yielded the littermate progeny with gross phenotypes representative of wild type (+/+), Atp2a1^tm1Dhm/Atpa2a1⁺ (+/-), and Atp2a1^tm1Dhm/Atp2a1^tm1Dhm (-/-) newborn mice. Note the similar size and normal appearance of the littermates, except that the two homozygous mice are cyanotic and appear light purple in color.

Copyright

This image is from Pan Y, J Biol Chem 2003 Apr 11;278(15):13367-75 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:82947

Associated Alleles

Symbol	Name
Atp2a1^tm1Dhm	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1; targeted mutation 1, David H MacLennon

Associated Genotypes

Allelic Composition	Genetic Background
Atp2a1^tm1Dhm/Atp2a1^tm1Dhm	involves: CD-1