Phenotype Image Detail

Image

Caption

Transmission electron microscopy of wild-type (+/+) and Lox^tm1Ikh/Lox^tm1Ikh (-/-) thoracic aortas. Disordered and fragmented elastic fibers in mutant thoracic aortas are seen by transmission electron microscopy (x3000 and x7000 magnification as shown on the left). The arrows point to elastic lamellae. L represents the lumen of the aorta.

Copyright

This image is from Hornstra IK, J Biol Chem 2003 Apr 18;278(16):14387-93 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:82926

Associated Alleles

Symbol	Name
Lox^tm1Ikh	lysyl oxidase; targeted mutation 1, Ian K Hornstra

Associated Genotypes

Allelic Composition	Genetic Background
Lox^tm1Ikh/Lox^tm1Ikh	involves: 129X1/SvJ * C57BL/6J