Phenotype Image Detail

Image

Caption

Morphology and phenotype of peritoneal mast cells from Srgn^tm1Mabr/Srgn^tm1Mabr mice. A: Cytospin slides were prepared from wild-type (+/+) and Srgn^tm1Mabr/Srgn^tm1Mabr (-/-) peritoneal cells and were stained with May Grunwald/Giemsa. Colored arrows indicate the presence of macrophages (green), lymphocytes (black) and mast cells (MCs, red), respectively. Note the absence of densely stained MCs in the mutant population and the presence in mutant populations of cells containing large empty vesicles.

Copyright

This image is from Abrink M, J Biol Chem 2004 Oct 24;279(39):40897-905 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:93338

Associated Alleles

Symbol	Name
Srgn^tm1Mabr	serglycin; targeted mutation 1, Magnus Abrink

Associated Genotypes

Allelic Composition	Genetic Background
Srgn^tm1Mabr/Srgn^tm1Mabr	involves: 129X1/SvJ