Phenotype Image Detail

Image

Caption

The fourth pair of mammary glands was isolated, fixed and whole-mounted from 5 week old (A and B), 10 week old (C-F), 15 week old (G and H) wild type or Ncoa6^tm1Jkr/Ncoa6^tm1Jkr Tg(MMTV-cre)FMam/? mice. Note that the PRIP deficiency (B,D,F and H) caused defective branching from early puberty (B) to the end of puberty (D,F) and persisted after puberty (H). E and F represent higher magnification of the gland structures in panels C and D, respectively.

Copyright

This image is from Qi C, J Biol Chem 2004 Aug 6;279(32):33696-701 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:121207

Associated Alleles

Symbol	Name
Ncoa6^tm1Jkr	nuclear receptor coactivator 6; targeted mutation 1, Janardan K Reddy
Tg(MMTV-cre)FMam	transgene insertion F, Lothar Hennighausen

Associated Genotypes

Allelic Composition	Genetic Background
Ncoa6^tm1Jkr/Ncoa6^tm1Jkr Tg(MMTV-cre)FMam/?	involves: 129P2/OlaHsd * FVB