Phenotype Image Detail

Image

Caption

Morphology of Ncoa6^tm1Jkr/Ncoa6^tm1Jkr Tg(MMTV-cre)FMam/? glands on the 15th day of pregnancy. The fourth inguinal mammary glands from wild-type (A and C) and Ncoa6^tm1Jkr/Ncoa6^tm1Jkr Tg(MMTV-cre)FMam/? mice (B and D) were isolated and whole-mounted. Note that mutant glands had underdeveloped lobuloalveolar structures with smaller and fewer alveoli. C and D represent higher magnification of the glands in panels A and B, respectively.

This image is from Qi C, J Biol Chem 2004 Aug 6;279(32):33696-701 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:121207

Associated
Alleles

Symbol	Name
Ncoa6^tm1Jkr	nuclear receptor coactivator 6; targeted mutation 1, Janardan K Reddy
Tg(MMTV-cre)FMam	transgene insertion F, Lothar Hennighausen

Associated
Genotypes

Allelic Composition	Genetic Background
Ncoa6^tm1Jkr/Ncoa6^tm1Jkr Tg(MMTV-cre)FMam/?	involves: 129P2/OlaHsd * FVB

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