Phenotype Image Detail

Image

Caption

A: Faxitron analysis of the craniofacial region of 8 week old Ambn^tm1Nid/Ambn⁺ (+/-) and Ambn^tm1Nid/Ambn^tm1Nid (-/-) mice. Boxed areas were enlarged in B, 1-3. B: High magnification of incisor tips (1), bottom incisors and alveolar bone space (2), and bottom molars (3). Round incisor tips, wider incisor-alveolar bone space, and a flat occlusal plane are observed in homozygous mutant mice. Arrows indicate incisor tips, incisor-alveolar bone space, and occlusal planes. inc, incisor; alv, alveolar bone. C: CT-scan analysis of top first molar of heterozygous and homozygous mutant mice. E, enamel; D, dentin; P, pulp. D: SEM analysis of incisor. E, enamel; D, dentin; p, pulp, dE, defective enamel.

Copyright

This image is from Fukumoto S, J Cell Biol 2004 Dec 6;167(5):973-83, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:94844

Associated Alleles

Symbol	Name
Ambn^tm1Nid	ameloblastin; targeted mutation 1, Yoshihiko Yamada

Associated Genotypes

Allelic Composition	Genetic Background
Ambn^tm1Nid/Ambn^tm1Nid	involves: 129S1/Sv * 129X1/SvJ * C57BL/6