Phenotype Image Detail

Image

Caption

Testes from 8 week old wild-type (+/+) and Sycp2^tm1Jw/Sycp2^tm1Jw (-/-) mice were used for histological and apoptosis analyses. A: Wild-type seminiferous tubule contains a full spectrum of germ cells; spermatogonia, pachytene spermatocytes (PS), round spermatids (RS), and elongated spermatids (ES). B-D: Three types of tubules observed in mutant testis. B: In type I tubules, multiple layers of zygotene-like spermatocytes (arrows) are present. C: In type II tubules, multiple layers of heavily eosin-stained cells (arrows) are present. D: In type III tubules, only a single layer of spermatogonia and Sertoli cells are present. E: Apoptosis of spermatocytes in type II mutant tubules. Arrows indicate one or two layers of brown-stained apoptotic cells. Bars: 50 um.

Copyright

This image is from Yang F, J Cell Biol 2006 May 22;173(4):497-507, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:111287

Associated Alleles

Symbol	Name
Sycp2^tm1Jw	synaptonemal complex protein 2; targeted mutation 1, Jeremy Wang

Associated Genotypes

Allelic Composition	Genetic Background
Sycp2^tm1Jw/Sycp2^tm1Jw	involves: 129S4/SvJae * C57BL/6