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Caption | Lack of increased intestinal apoptosis or basement membrane disruption in Itgb1tm1Efu/Itgb1tm1Efu Tg(Vil1-cre)997Gum/0 mice. A and B: Immunohistochemical detection of cleaved caspase 3 (brown; arrows) positive intestinal epithelial cells (IECs) in small intestine of control (wt) and Itgb1tm1Efu/Itgb1tm1Efu Tg(Vil1-cre)997Gum/0 (ko) mice. Bars, 0.05 mm. C-F: Transmission electron micrographs showing the basement membranes (arrows) in the ileum of control and mutant mice. SC, stromal cell; n, nucleus. G: Gastrointestinal tracts resected from mutant (top) and Itgb1tm1Efu/Itgb1tm1Efu (bottom) mice from Fig. 1E. H: The inset shows the larger diameters of the distal small intestine and proximal large intestine (black arrowheads) of the mutant mouse. | ||||||
Copyright | This image is from Jones RG, J Cell Biol 2006 Nov 6;175(3):505-14, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:119155 | ||||||
Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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