Phenotype Image Detail

Image

Caption

Testes and epididymides from 7 week old wild-type (+/+) and Tex15^tm1Jw/Tex15^tm1Jw (-/-) mice were subject to histological analysis. A: A wild-type seminiferous tubule contains a full spectrum of germ cells; zygotene spermatocytes (Z), pachytene spermatocytes (P), and elongating spermatids (ES). B: In some mutant seminiferous tubules, two to three layers of zygotene-like spermatocytes (arrows) are present. C: Mutant tubules with large but lightly stained degenerating spermatocytes (arrows). D: Mutant tubules with only a single layer of early spermatogenic and Sertoli cells (arrow). E: Wild-type epididymal tubules were full of spermatozoa. F: Epididymal tubules from mutant mice were devoid of germ cells. Bar: 50 um.

Copyright

This image is from Yang F, J Cell Biol 2008 Feb 25;180(4):673-9, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:135578

Associated Alleles

Symbol	Name
Tex15^tm1Jw	testis expressed gene 15 meiosis and synapsis associated; targeted mutation 1, Jeremy Wang

Associated Genotypes

Allelic Composition	Genetic Background
Tex15^tm1Jw/Tex15^tm1Jw	involves: 129S4/SvJae * C57BL/6