Phenotype Image Detail

Image

Caption

Sections through control (Panels A and C) and Ada^tm1Mw/Ada^tm1Mw Tg(PLADA)4118Rkmb/0 (panels B and D) thymuses stained with hematoxylin and eosin. c, cortex; m, medulla; h, Hassel's corpuscles; large arrows denote cortical medullary junction. Hematoxylin and eosin stained sections through control (panels E and F) and mutant spleens. w, white pulp; r, red pulp; m, megakarocytes; t, trabeculae. Scale bar in F= 1 mm for A,B,E and F. Scale bar in H= 100 um for C,D,G and H.

Copyright

This image is from Blackburn MR, J Biol Chem 1998 Feb 27;273(9):5093-100 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:73418

Associated Alleles

Symbol	Name
Ada^tm1Mw	adenosine deaminase; targeted mutation 1, Maki Wakamiya
Tg(PLADA)4118Rkmb	transgene insertion 4118, Michael R Blackburn

Associated Genotypes

Allelic Composition	Genetic Background
Ada^tm1Mw/Ada^tm1Mw Tg(PLADA)4118Rkmb/0	involves: 129S7/SvEvBrd * C57BL/6