Phenotype Image Detail

Image

Caption

Phenotype of three Pik3ca^tm1Nbm/Pik3ca^tm1Nbm embryos. Hemorrhage is observed at the forehead, snout and other parts of the body. A and B represent the most typical examples of the distribution of hemorrhage. C was a less typical example in which a hemorrhagic bubble was observed on the dorsum of the embryo.

Copyright

This image is from Bi L, J Biol Chem 1999 Apr 16;274(16):10963-8 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:54237

Associated Alleles

Symbol	Name
Pik3ca^tm1Nbm	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; targeted mutation 1, Robert L Nussbaum

Associated Genotypes

Allelic Composition	Genetic Background
Pik3ca^tm1Nbm/Pik3ca^tm1Nbm	involves: 129S6/SvEvTac