Phenotype Image Detail

Image

Caption

Ultrastructural changes in capillaries. Electron microscopy of heart capillaries from a wild-type mouse (A) and Col15a1^tm1Pih/Col15a1^tm1Pih mouse (B) with swollen endothelial cells (asterisks). The lumen is indicated by a white arrow. Skeletal muscle capillaries from a wild-type (C), and a mutant mouse (D) showing luminal narrowing and folding of endothelial cells.

Copyright

This image is from Eklund L, Proc Natl Acad Sci U S A 2001 Jan 30;98(3):1194-9. Copyright 2001 National Academy of Sciences, U.S.A. J:67212

Associated Alleles

Symbol	Name
Col15a1^tm1Pih	collagen, type XV, alpha 1; targeted mutation 1, Taina Pihlajaniemi

Associated Genotypes

Allelic Composition	Genetic Background
Col15a1^tm1Pih/Col15a1^tm1Pih	involves: 129S1/Sv * 129X1/SvJ