Phenotype Image Detail

Image

Caption

Gross morphology of Por^tm1Cbk/Por^tm1Cbk embryos reveals a spectrum of abnormalities. The asterisk indicates the boundaries of the open neural tube. The arrow indicates bleeding along the neural folds. Arrowhead, the enlarged pericardial cavity. fb, forebrain; mb, midbrain; hb, hindbrain; ba, branchial arches; h, heart; t, tail; hl, hind limb bud; fl, fore limb bud. A, wild-type (+/+) embryo; B, Type I Por^tm1Cbk/Por^tm1Cbk (-/-) embryo; C, Type II mutant embryo.

Copyright

This image is from Shen AL, J Biol Chem 2002 Feb 22;277(8):6536-41 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:74666

Associated Alleles

Symbol	Name
Por^tm1Cbk	cytochrome p450 oxidoreductase; targeted mutation 1, Charles B Kasper

Associated Genotypes

Allelic Composition	Genetic Background
Por^tm1Cbk/Por^tm1Cbk	involves: 129S1/Sv * 129X1/SvJ * C57BL/6