Phenotype Image Detail

Image

Caption

Scanning electron microscopy of E10.5 wild-type (+/+) and Por^tm1Cbk/Por^tm1Cbk (-/-) embryos. The asterisk indicates the boundaries of the open neural tube. Arrowhead, exencephaly. fb, forebrain; mb, midbrain, hb, hindbrain; e, eye; ba, branchial arches; fn, fronto-nasal region; A, wild-type enbryo. B and C, failure of neural tube closure in mutant embryos.

Copyright

This image is from Shen AL, J Biol Chem 2002 Feb 22;277(8):6536-41 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:74666

Associated Alleles

Symbol	Name
Por^tm1Cbk	cytochrome p450 oxidoreductase; targeted mutation 1, Charles B Kasper

Associated Genotypes

Allelic Composition	Genetic Background
Por^tm1Cbk/Por^tm1Cbk	involves: 129S1/Sv * 129X1/SvJ * C57BL/6