Phenotype Image Detail

Image

Caption

A: Male and female Irak3^tm1Flv/Irak3^tm1Flv (IRAK-M^-/-) mice are smaller than wild-type (IRAK-M^+/+) mice; n=10. B: microCT analysis of distal femurs from 4 month old mutant and wild-type male mice. Note the paucity of the trabeculae inside the bone in mutant mice. The wider diameter of the bone sections measures ~3 mm. Bar, 1 mm. C: Toluidine blue staining of sections from epiphyseal bones from 4 month old mutant and wild-type male mice. Bar, 1 mm. D: TRAP staining of sections from epiphyseal bones from 4 month old mutant and wild-type male mice. Bar, 200 um.

Copyright

This image is from Li H, J Exp Med 2005 Apr 4;201(7):1169-77, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:98035

Associated Alleles

Symbol	Name
Irak3^tm1Flv	interleukin-1 receptor-associated kinase 3; targeted mutation 1, Richard A Flavell

Associated Genotypes

Allelic Composition	Genetic Background
Irak3^tm1Flv/Irak3^tm1Flv	involves: 129S1/Sv * C57BL/6