Phenotype Image Detail

Image

Caption

A: Body weight gain of male mice fed a high fat diet for 23 weeks. Eight week old male mice (n=6 for each group) were fed a high fat diet (45% w/w) for 23 weeks. Body weights were recorded weekly. The increases in body weights were calculated based on the initial body weight at day 0 of high fat feeding and expressed as the percentage of increase. B Absolute fat mass of white adipose tissue (WAT) was significantly reduced in 31 week old male Pnrc2^tm1Shch/Pnrc2^tm1Shch (PNRC2^-/-) mice compared with wild-type (WT) mice at the end of high fat feeding. Data represent the mean +/- S.D. (n = 6/genotype). Histology of WAT (C), liver (D) and brown adipose tissue (BAT, E) of mice fed high fat diet (*,p<0.05 and **,p<0.001).

Copyright

This image is from Zhou D, J Biol Chem 2008 Jan 4;283(1):541-53 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:130294

Associated Alleles

Symbol	Name
Pnrc2^tm1Shch	proline-rich nuclear receptor coactivator 2; targeted mutation 1, Shiuan Chen

Associated Genotypes

Allelic Composition	Genetic Background
Pnrc2^tm1Shch/Pnrc2^tm1Shch	involves: 129S1/Sv * C57BL/6