Gene Expression Image Detail

Reference

Figure

ID

J:143398 Homma S, et al., Gene Expr Patterns. 2009 Jan;9(1):1-26

3

MGI:3829791

Image

Caption

Whole-mount preparations (A-C), or tissue sections (D-N). (A-C) Lateral views. te, telencephalon; di, diencephalon; me, mesencephalon; rh, rhombencephalon; sc, spinal cord; eye, optic cup; Vth, trigeminal ganglia; VIIIth, cochlear ganglia; Xth, superior ganglia of the vagus nerve; drg, dorsal root ganglia; and br, branchial arch. (D-F) Frontal sections through the most anterior telencephalon (te), showing LINGO1 (D), LINGO2 (E), and LINGO4 (F) expression in the nasal placode (np). Hatched lines are the midline of the telencephalon. (G) A transverse section through the telencephalon (te), floor of the diencephalon (di), and mesencephalon (me). Expression of LINGO1 is also seen in the optic cup (eye) and trigeminal ganglia (Vth). (H) LINGO2 hybridization in a frontal section through the mesencephalon (me) and rhombencephalon (rh). (I) A transverse section through the rhombencephalon (rh), showing LINGO1 expression in the rhombencephalon (arrowheads) and cochlear ganglia (VIIIth). ot, otocyst. (J) A frontal section through the first and second branchial arches (1st br and 2nd br). (K) Arrowheads indicate LINGO4 expression in a small region near the floor plate, the fourth ventricle (4thv). (L) Arrowheads indicate LINGO1 expression in the peritoneal lining. li, liver and sp, spinal cord. (M) LINGO1 expression in a transverse section through the spinal cord and dorsal root ganglia (drg). Arrowheads indicate LINGO1 expression in apparent post-mitotic neurons located in the periphery of the spinal cord. (N) LINGO4 expression in a transverse section of the spinal cord. Arrowheads indicate expression in a small region of the ventricular layer close to the floor plate (fp). The outer boundary and midline are indicated by hatched lines. (O) Summary of LINGO expression is shown in a schematic drawing of an obliquely parasagittal plane of E10 mouse embryo. Orange dots, LINGO1; green dots, LINGO2; and blue dots, LINGO4. The approximate levels and orientations of the sections are shown by thick lines with corresponding alphabets.

Copyright

Reprinted with permission from Elsevier from doi:10.1016/j.gep.2008.09.004 Gene Expr Patterns 9: 1-26, Homma S; Shimada T; Hikake T; Yaginuma H, Expression pattern of LRR and Ig domain-containing protein (LRRIG protein) in the early mouse embryo. Copyright 2009

Associated
Assays

Label	Assay & Result Details (Gene Symbol)	Spatial Mapping
A	MGI:3830066 (Lingo1)
B	MGI:3830070 (Lingo2)
C	MGI:3830072 (Lingo3)
D	MGI:3830066 (Lingo1)
E	MGI:3830070 (Lingo2)
F	MGI:3830073 (Lingo4)
G	MGI:3830066 (Lingo1)
H	MGI:3830070 (Lingo2)
I	MGI:3830066 (Lingo1)
J	MGI:3830066 (Lingo1)
K	MGI:3830073 (Lingo4)
L	MGI:3830066 (Lingo1)
M	MGI:3830066 (Lingo1)
N	MGI:3830073 (Lingo4)