Phenotype Image Detail

Image

Caption

Phenotype of Vps33a^bf/Vps33a^bf (bf/bf) mutant mice. A: Coat color hypopigmentation in adult mutant versus wild-type C57BL/6J mice. B: Reduced size and number of melanosomes in the eyes of mutant (lower) versus wild-type (upper) mice. The dotted lines represent demarcation between retinal pigment epithelium (above) and choroid (below). Scale bar: 2um. C: Reduced collagen-mediated platelet aggregation (solid line) and dense granule ATP secretion (dotted line) in mutant versus wild-type mice. The arrows indicate the time of addition of collagen.

Copyright

This image is from Suzuki T, Proc Natl Acad Sci U S A 2003 Feb 4;100(3):1146-50. Copyright 2003 National Academy of Sciences, U.S.A. J:81830

Associated Alleles

Symbol	Name
Vps33a^bf	VPS33A CORVET/HOPS core subunit; buff

Associated Genotypes

Allelic Composition	Genetic Background
Vps33a^bf/Vps33a^bf	C57BL/6J-Vps33a^bf